Projects
decoration

Discovery of novel niche factors to improve long-term stem cell transplantation in bone marrow failure syndromes. 

2023- 2025 (Fellowship): Discovery of novel niche factors to improve long-term stem cell transplantation in bone marrow failure syndromes. Dr Vashe Chandrakanthan, The University of Adelaide.

For many patients with Bone Marrow Failure Syndromes, a bone marrow transplant is the only hope for a cure. However, for a transplant to be effective the transplanted stem cells need to mature, and develop into long-term healthy adult stem cells. If this doesn’t happen, the transplant could fail.

It’s vital that there are more treatment options to increase the number of marrow-stimulating molecules and improve outcomes for patients with severe marrow failure. Dr Chandrakanthan’s research looks at developing a growth factor based treatment to help the transplanted stem cells to mature and produce healthy blood. This research could potentially transform the transplantation management of patients with Bone Marrow Failure Syndromes.

Related Projects

Improving outcomes for Australian patients and families with bone marrow failure related diseases through comprehensive clinicogenomic care and collaborative research.

2021-2023 (Fellowship): Improving outcomes for Australian patients and families with bone marrow failure related diseases through comprehensive clinicogenomic care and collaborative research. Dr Lucy Fox, Peter MacCallum Cancer Centre.

Read more

High resolution definition of the mechanisms of poor graft function following allogeneic haematopoietic stem cell transplantation

2023 – 2026 (Fellowship): New Investigator PhD Scholarship, co-funded with the Haematology Society of Australia and New Zealand. High resolution definition of the mechanisms of poor graft function following allogeneic haematopoietic stem cell ...

Read more

Determining genetic and epigenetic drivers of gene expression changes in blood cells.

2020-2023 (Fellowship): The Alex Gadomski PhD Scholarship in Medical Research, co-funded with the University of Tasmania. Determining genetic and epigenetic drivers of gene expression changes in blood cells. Ariel Simpson, Menzies Institute for ...

Read more

Modelling consequences of cell abundance, heterogeneity and origin for autologous cell therapy in genetic bone marrow failure syndromes.

2020-2022 (Fellowship): Modelling consequences of cell abundance, heterogeneity and origin for autologous cell therapy in genetic bone marrow failure syndromes. Dr Parvathy Venugopal, Centre for Cancer Biology / University of South Australia. Dr ...

Read more

Sign up to be the first to hear about our upcoming News & Events