Projects
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Discovery of novel niche factors to improve long-term stem cell transplantation in bone marrow failure syndromes. 

2023- 2025 (Fellowship): Discovery of novel niche factors to improve long-term stem cell transplantation in bone marrow failure syndromes. Dr Vashe Chandrakanthan, The University of Adelaide.

For many patients with Bone Marrow Failure Syndromes, a bone marrow transplant is the only hope for a cure. However, for a transplant to be effective the transplanted stem cells need to mature, and develop into long-term healthy adult stem cells. If this doesn’t happen, the transplant could fail.

It’s vital that there are more treatment options to increase the number of marrow-stimulating molecules and improve outcomes for patients with severe marrow failure. Dr Chandrakanthan’s research looks at developing a growth factor based treatment to help the transplanted stem cells to mature and produce healthy blood. This research could potentially transform the transplantation management of patients with Bone Marrow Failure Syndromes.

Related Projects

High resolution definition of the mechanisms of poor graft function following allogeneic haematopoietic stem cell transplantation

2023 – 2026 (Fellowship): New Investigator PhD Scholarship, co-funded with the Haematology Society of Australia and New Zealand. High resolution definition of the mechanisms of poor graft function following allogeneic haematopoietic stem cell ...

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Bone Marrow Failure Syndromes in Australia: improving diagnosis to inform strategies for better care and outcomes. 

2019-2020 (Doctoral Degree Fellowship): Bone Marrow Failure Syndromes in Australia: improving diagnosis to inform strategies for better care and outcomes. Dr Lucy Fox, The University of Melbourne. Dr Lucy Fox is completing a higher degree ...

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Utility of a neurobehavioural assessment for treatment planning, educational, and family support for children undergoing bone marrow transplant for non-malignant disease. 

2023-2025 (Fiona Riewoldt Nursing/Allied Health Fellowship): Utility of a neurobehavioural assessment for treatment planning, educational, and family support for children undergoing bone marrow transplant for non-malignant ...

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Modelling consequences of cell abundance, heterogeneity and origin for autologous cell therapy in genetic bone marrow failure syndromes.

2020-2022 (Fellowship): Modelling consequences of cell abundance, heterogeneity and origin for autologous cell therapy in genetic bone marrow failure syndromes. Dr Parvathy Venugopal, Centre for Cancer Biology / University of South Australia. Dr ...

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