Discovery of novel niche factors to improve long-term stem cell transplantation in bone marrow failure syndromes.
2023- 2025 (Fellowship): Discovery of novel niche factors to improve long-term stem cell transplantation in bone marrow failure syndromes. Dr Vashe Chandrakanthan, The University of Adelaide.
For many patients with Bone Marrow Failure Syndromes, a bone marrow transplant is the only hope for a cure. However, for a transplant to be effective the transplanted stem cells need to mature, and develop into long-term healthy adult stem cells. If this doesn’t happen, the transplant could fail.
It’s vital that there are more treatment options to increase the number of marrow-stimulating molecules and improve outcomes for patients with severe marrow failure. Dr Chandrakanthan’s research looks at developing a growth factor based treatment to help the transplanted stem cells to mature and produce healthy blood. This research could potentially transform the transplantation management of patients with Bone Marrow Failure Syndromes.
Related Projects
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2021-2023 (Fellowship): Improving outcomes for Australian patients and families with bone marrow failure related diseases through comprehensive clinicogenomic care and collaborative research. Dr Lucy Fox, Peter MacCallum Cancer Centre.
Read moreHigh resolution definition of the mechanisms of poor graft function following allogeneic haematopoietic stem cell transplantation
2023 – 2026 (Fellowship): New Investigator PhD Scholarship, co-funded with the Haematology Society of Australia and New Zealand. High resolution definition of the mechanisms of poor graft function following allogeneic haematopoietic stem cell ...
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