Projects
decoration

Novel immunological assessment of Aplastic Anaemia and post transplant Graft Dysfunction for the purposes of targeted therapeutic intervention.  

2019-2023 (Co-funded VCA/Maddie Riewoldt’s Vision International Travelling Fellowship): Novel immunological assessment of Aplastic Anaemia and post transplant Graft Dysfunction for the purposes of targeted therapeutic intervention. Dr Ashvind Prabahran, Melbourne Health.

Aplastic Anaemia results from the immune system attacking the bone marrow spontaneously. Poor Graft Function (PGF) refers to a type of bone marrow failure that occurs after bone marrow transplantation when, despite the recipient’s bone marrow being filled with 100% donor cells, the donor bone marrow fails to function. PGF results in significant complications for patients after bone marrow transplant and further understanding of this condition is required. Aplastic Anaemia and PGF both result in low blood cell levels and there may be similarities between these two conditions. If we can confirm similarities with Aplastic Anaemia, this will allow the faster development of therapies in both PGF and Aplastic Anaemia, as patients with PGF and Aplastic Anaemia can be studied together in future clinical trials.

Related Projects

Towards targeted treatments for Fanconi Anaemia 

2017 – 2019 Fellowship / 2017 Grant-in-Aid, Towards targeted treatments for Fanconi Anaemia, Associate Professor Wayne Crismani, St Vincents Institute for Medical Research Fanconi Anaemia is an inherited disorder which can lead to bone ...

Read more

Modelling consequences of cell abundance, heterogeneity and origin for autologous cell therapy in genetic Bone Marrow Failure Syndromes.

2020-2023 (Fellowship): Modelling consequences of cell abundance, heterogeneity and origin for autologous cell therapy in genetic Bone Marrow Failure Syndromes. Dr Parvathy Venugopal, Centre for Cancer Biology / University of South Australia. In ...

Read more

Improving capability and capacity of nurses to assess and manage young people with symptoms associated with acquired and inherited bone marrow failure syndromes. 

2022-2024 (Fiona Riewoldt Nursing/Allied Health Fellowship): Improving capability and capacity of nurses to assess and manage young people with symptoms associated with acquired and inherited bone marrow failure syndromes. Rachel Edwards, ...

Read more

Clinical genomic and molecular determinants of outcome in patients with Bone Marrow Failure Syndromes

2018-2021 (Doctoral Degree Fellowship): Clinical, genomic and molecular determinants of outcome in patients with Bone Marrow Failure Syndromes, Dr Lucy Fox, The University of Melbourne. This project is the first scholarship in Australia to ...

Read more

Sign up to be the first to hear about our upcoming News & Events