Clinical genomic and molecular determinants of outcome in patients with Bone Marrow Failure Syndromes

2018-2021 (Doctoral Degree Fellowship): Clinical, genomic and molecular determinants of outcome in patients with Bone Marrow Failure Syndromes, Dr Lucy Fox, The University of Melbourne.

This project is the first scholarship in Australia to support a dedicated Doctor of Medical Science scholar to focus on describing, understanding and improving diagnosis of Bone Marrow Failure Syndromes using genomics evaluation. More accurate diagnosis of Bone Marrow Failure Syndromes using genomics evaluation underpins targeted treatment/s which will be associated with a greater chance of cure while avoiding harms and costs of inappropriate therapies. Working closely with the Aplastic Anaemia Registry (AAR) team, this new research role will also provide a valuable clinical resource to the AAR project team and contribute to analysis of Australian data for presentation and publication.

Related Projects

Modelling consequences of cell abundance, heterogeneity and origin for autologous cell therapy in genetic Bone Marrow Failure Syndromes.

2020-2023 (Fellowship): Modelling consequences of cell abundance, heterogeneity and origin for autologous cell therapy in genetic Bone Marrow Failure Syndromes. Dr Parvathy Venugopal, Centre for Cancer Biology / University of South Australia. In ...

A preclinical trial of next generation gene editing for the prevention of bone marrow failure in Fanconi Anaemia

2023- 2025 (Fellowship): The inaugural Captain Courageous Fellowship. A preclinical trial of next generation gene editing for the prevention of bone marrow failure in Fanconi Anaemia. Dr Astrid Glaser at the Genome Stability Unit of St Vincent’s ...

Improving outcomes for Australian patients and families with bone marrow failure related diseases through comprehensive clinicogenomic care and collaborative research.

2021-2024 (Fellowship): Improving outcomes for Australian patients and families with bone marrow failure related diseases through comprehensive clinicogenomic care and collaborative research. Dr Lucy Fox, Peter MacCallum Cancer Centre. Dr Lucy ...

Dissecting immune dysregulation in acquired bone marrow failure syndromes to identify new therapeutic leads.

2022-2025 (Fellowship): Dissecting immune dysregulation in acquired Bone Marrow Failure Syndromes to identify new therapeutic leads. Associate Professor Rachel Koldej, ACRF Translational Research Laboratory, Melbourne Health. Bone Marrow Failure ...