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Current Projects

CRE in Bone Marrow Biology Research Portfolio

Completed and current research projects: 

  • 2015 – 2018: The Australian Aplastic Anaemia Registry as a Means for Advancing Effective Treatment of Aplastic Anaemia Transfusion Outcomes Research Collaborative (TORC). TORC is a consortium of members of Monash University Department of Epidemiology and Preventive Medicine at The Alfred Hospital, along with members of the Red Cross Blood Service. For further information, please visit the registry's website
  • 2016-2019 (Fellowship): Part 1 - Prevention and treatment of bone marrow failure in Fanconi anaemia and other inherited disorders. Dr Wayne Crismani, St Vincent’s Institute of Medical Research
  • 2017-2019 (Grant): Part 2 - Prevention and treatment of bone marrow failure in Fanconi anaemia and other inherited disorders. Dr Wayne Crismani, St Vincent's Institute of Medical Research
  • 2016-2018 (Grant): Identification of miRNA biomarkers which play a functional role in disease pathogenesis and are predictive of inferior outcomes in AA/MDS. Dr Lynette Chee, The Royal Melbourne Hospital/Melbourne Health
  • 2017-2020 (Fellowship): Genome editing of haematopoietic stem and progenitor cells to uncover novel therapeutics for aplastic anaemia and other bone marrow failure syndromes. Dr Yih-Chih Chan and Professor Mark Dawson, The University of Melbourne through the Sir Peter MacCallum Department of Oncology
  • 2017-2019 (Grant): Predicting malignant transformation of bone marrow failure syndromes using longitudinal targeted sequencing of peripheral blood and cell-free DNA (cfDNA). Dr Piers Blombery, Peter MacCallum Cancer Centre
  • 2018-2020 (Grant): Influences of clonal haematopoiesis in allogeneic bone marrow transplantation. Dr Paul Yeh and Professor Mark Dawson, The University of Melbourne
  • 2019-2020 (Doctoral Degree Fellowship): Bone Marrow Failure Syndromes in Australia: improving diagnosis to inform strategies for better care and outcomes. Dr Lucy Fox, The University of Melbourne
  • 2018-2020 (Grant): Identifying therapeutics which can be repurposed for the treatment of Myelodysplastic Syndromes and other Bone Marrow Failure Disorders. Dr Amee George, The Australian National University
  • 2018-2020 (Grant): Using induced pluripotent stem cells to find causes and cures for bone marrow failure in children and young adults. Professor Andrew Elefanty, Murdoch Children's Research Institute
  • 2018-2020 (Grant): Discovering new genes and mutations that cause failure of bone marrow neutrophil production. Professor Graham Lieschke, Australian Regenerative Medicine Institute/Monash University and The Royal Melbourne Hospital
  • 2018-2020 (Co-funded VCA/MRV International Fellowship): International Travelling Fellowship. Novel immunological assessment of Aplastic Anaemia and post transplant Graft Dysfunction for the purposes of targeted therapeutic intervention. Dr Ashvind Prabahran, The Royal Melbourne Hospital/Melbourne Health
  • 2018-2020 (co-funded Snowdome/Gunn Family/Maddie's Vision Fellowship): The Gunn Family National Fellowship for Career Development in Research - Women in Haematology. Novel blood biomarkers for predicting bone marrow failure in Myeloproliferative neoplasms. Dr Belinda Guo, University of Western Australia
  • 2019-2021 (Fellowship): The Alex Gadomski Fellowship. Functional Interrogation of Loci associated with the Regulation of Haematopoiesis. Dr Kirsten Fairfax, Menzies Institute for Medical Research and University of Tasmania.
  • 2019-2020 (Grant): Extension to The Australian Aplastic Anaemia and other Bone Marrow Failure Syndromes Registry. Professor Erica Wood, Monash University Department of Epidemiology and Preventative Medicine. For further information, please visit the registry's website
  • 2019-2021 (Grant): Evaluating Multidisciplinary Bone Marrow Failure Syndrome Care - a prospective observational clinical trial offering comprehensive diagnostic genomic evaluation, multidisciplinary case review and multidisciplinary clinical care. PIs Dr Lucy Fox and Dr Piers Blombery. The University of Melbourne and Clinical Haematology, Peter MacCallum Cancer Centre and The Royal Melbourne Hospital
  • 2020 -2022 (Fellowship): Modelling consequences of cell abundance, heterogeneity and origin for autologous cell therapy in genetic bone marrow failure syndromes. Dr Parvathy Venugopal, Centre for Cancer Biology / University of South Australia
  • 2020 -2021 (Grant-in-Aid): Establishing an in vivo humanised mouse model for telomere related bone marrow failure syndromes. Professor Tracy Bryan, Children's Medical Research Institute
  • 2020 -2021 (Grant-in-Aid): Microenvironmental determinants of Aplastic Anaemia progression to MDS / AML. Dr Rachel Koldej, ACRF Translational Research Laboratory, Melbourne Health
  • 2020 -2023 (Fellowship): The Alex Gadomski PhD Scholarship in Medical Research. Co-funded with the University of Tasmania. Ariel Simpson, Menzies Institute for Medical Research
  • 2020 -2023 (Grant): The Australian Bone Marrow Failure Biobank. Professor Melissa Southey, Biobanking Victoria, Monash University
  • 2020 -2023 (Program): The RESELECT Trial - REscuing bone marrow function in patients with relapsed aplaStic anaEmia and/or bone marrow failure post aLlogeneic stEm Cell Transplantation. PI Professor David Ritchie
  • 2020 -2022 (GIA): Using whole genome sequence analysis to find answers for unsolved cases of inherited bone marrow failure syndrome. Dr Piers Blombery, The University of Melbourne
  • 2020 -2021 (GIA): Curation of the DIAAMOND-based Aplastic Anaemia Biobank. Associate Professor Stephen Ting, Monash University
  • 2021 - 2023 (Fellowship): Improving outcomes for Australian patients and families with bone marrow failure related diseases through comprehensive clinicogenomic care and collaborative research. Dr Lucy Fox, Peter MacCallum Cancer Centre
Collaborative Research Institutions
                          


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