Projects
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High resolution definition of the mechanisms of poor graft function following allogeneic haematopoietic stem cell transplantation

2023-2028 (Maddie Riewoldt’s Vision/Haematology Society of Australia and New Zealand Scholarship) High resolution definition of the mechanisms of poor graft function following allogeneic haematopoietic stem cell transplantation, Dr Daniel North, Weatherall Institute of Molecular Medicine.

Bone marrow transplants are often used as a treatment for Bone Marrow Failure Syndromes. But this treatment comes with a lot of risks and potential complications, such as poor graft function, infections, or requiring long-term blood transfusion support. Dr North’s project focuses on understanding poor graft function, a potentially life-threatening complication of transplants, by investigating its causes at a cellular level within the bone marrow environment.

By knowing more about why bone marrow transplants fail or result in complications, we can provide better treatments or even prevent them from occurring. This research project is proudly funded by Maddie Riewoldt’s Vision and Haematology Society of Australia and New Zealand.

Related Projects

Steps toward generating new molecular therapies for Bone Marrow Failure Syndromes

2020 – 2024 (Alex Gadomski Scholarship): Steps toward generating new molecular therapies for Bone Marrow Failure Syndromes, Ariel Simpson, Menzies Institute for Medical Research and University of Tasmania. The only established treatment ...

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Identification of microRNA biomarkers predictive of clinical outcomes in Aplastic Anaemia and Myelodysplastic Syndrome

2016 – 2019 (Grant-in-Aid) Identification of microRNA biomarkers predictive of clinical outcomes in Aplastic Anaemia and Myelodysplastic Syndrome, Dr Lynette Chee, Melbourne Health. DNA is the genetic material which provides the information that ...

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Outcomes of Haematopoietic Stem Cell Transplantation for Paediatric Patients with Severe Aplastic Anaemia (SAA) and Bone Marrow Failure (BMF) Syndromes.

2021-2022 (Grant-in-Aid): Outcomes of Haematopoietic Stem Cell Transplantation for Paediatric Patients with Severe Aplastic Anaemia (SAA) and Bone Marrow Failure (BMF) Syndromes. Dr Steven Keogh, Australasian Bone Marrow Transplant Recipient ...

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Towards targeted treatments for Fanconi Anaemia 

2017 – 2019 Fellowship / 2017 Grant-in-Aid, Towards targeted treatments for Fanconi Anaemia, Associate Professor Wayne Crismani, St Vincents Institute for Medical Research Fanconi Anaemia is an inherited disorder which can lead to bone ...

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