Projects
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High resolution definition of the mechanisms of poor graft function following allogeneic haematopoietic stem cell transplantation

2023-2028 (Maddie Riewoldt’s Vision/Haematology Society of Australia and New Zealand Scholarship) High resolution definition of the mechanisms of poor graft function following allogeneic haematopoietic stem cell transplantation, Dr Daniel North, Weatherall Institute of Molecular Medicine.

Bone marrow transplants are often used as a treatment for Bone Marrow Failure Syndromes. But this treatment comes with a lot of risks and potential complications, such as poor graft function, infections, or requiring long-term blood transfusion support. Dr North’s project focuses on understanding poor graft function, a potentially life-threatening complication of transplants, by investigating its causes at a cellular level within the bone marrow environment.

By knowing more about why bone marrow transplants fail or result in complications, we can provide better treatments or even prevent them from occurring. This research project is proudly funded by Maddie Riewoldt’s Vision and Haematology Society of Australia and New Zealand.

Related Projects

Steps toward generating new molecular therapies for Bone Marrow Failure Syndromes

2020 – 2024 (Alex Gadomski Scholarship): Steps toward generating new molecular therapies for Bone Marrow Failure Syndromes, Ariel Simpson, Menzies Institute for Medical Research and University of Tasmania. The only established treatment ...

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Functional interrogation of Loci associated with the regulation of haematopoiesis

2019-2021 (Fellowship): The Alex Gadomski Fellowship. Functional interrogation of Loci associated with the regulation of haematopoiesis. Dr Kirsten Fairfax, Menzies Institute for Medical Research and University of Tasmania. To understand bone ...

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Aplastic Anaemia Registry (AAR) and the Aplastic Anaemia and Other Bone Marrow Failure Syndromes Registry

2015-ongoing: The Australian Aplastic Anaemia and Other Bone Marrow Failure Syndromes Registry, Transfusion Research Unit, Monash University. The Aplastic Anaemia Registry (AAR), established in 2012, is a collaboration between the Transfusion ...

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A preclinical trial of next generation gene editing for the prevention of bone marrow failure in Fanconi Anaemia

2023- 2025 (Fellowship): The inaugural Captain Courageous Fellowship. A preclinical trial of next generation gene editing for the prevention of bone marrow failure in Fanconi Anaemia. Dr Astrid Glaser at the Genome Stability Unit of St Vincent’s ...

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