Projects
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High resolution definition of the mechanisms of poor graft function following allogeneic haematopoietic stem cell transplantation

2023-2028 (Maddie Riewoldt’s Vision/Haematology Society of Australia and New Zealand Scholarship) High resolution definition of the mechanisms of poor graft function following allogeneic haematopoietic stem cell transplantation, Dr Daniel North, Weatherall Institute of Molecular Medicine.

Bone marrow transplants are often used as a treatment for Bone Marrow Failure Syndromes. But this treatment comes with a lot of risks and potential complications, such as poor graft function, infections, or requiring long-term blood transfusion support. Dr North’s project focuses on understanding poor graft function, a potentially life-threatening complication of transplants, by investigating its causes at a cellular level within the bone marrow environment.

By knowing more about why bone marrow transplants fail or result in complications, we can provide better treatments or even prevent them from occurring. This research project is proudly funded by Maddie Riewoldt’s Vision and Haematology Society of Australia and New Zealand.

Related Projects

Steps toward generating new molecular therapies for Bone Marrow Failure Syndromes

2020 – 2024 (Alex Gadomski Scholarship): Steps toward generating new molecular therapies for Bone Marrow Failure Syndromes, Ariel Simpson, Menzies Institute for Medical Research and University of Tasmania. The only established treatment ...

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Using whole genome sequence analysis to find answers for unsolved cases of inherited Bone Marrow Failure Syndrome (iBMFS).

2020-2022 (Grant-in-Aid): Using whole genome sequence analysis to find answers for unsolved cases of inherited Bone marrow Failure Syndrome. Associate Professor Piers Blombery, The University of Melbourne. Inherited Bone Marrow Failure Syndromes ...

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A preclinical trial of next generation gene editing for the prevention of bone marrow failure in Fanconi Anaemia

2023- 2025 (Fellowship): The inaugural Captain Courageous Fellowship. A preclinical trial of next generation gene editing for the prevention of bone marrow failure in Fanconi Anaemia. Dr Astrid Glaser at the Genome Stability Unit of St Vincent’s ...

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Discovering new genes and mutations that cause failure of bone marrow neutrophil production. 

2018-2020 (Grant in aid): Discovering new genes and mutations that cause failure of bone marrow neutrophil production. Professor Graham Lieschke, Australian Regenerative Medicine Institute/Monash University and The Royal Melbourne Hospital. ...

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