Projects
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High resolution definition of the mechanisms of poor graft function following allogeneic haematopoietic stem cell transplantation

2023-2028 (Maddie Riewoldt’s Vision/Haematology Society of Australia and New Zealand Scholarship) High resolution definition of the mechanisms of poor graft function following allogeneic haematopoietic stem cell transplantation, Dr Daniel North, Weatherall Institute of Molecular Medicine.

Bone marrow transplants are often used as a treatment for Bone Marrow Failure Syndromes. But this treatment comes with a lot of risks and potential complications, such as poor graft function, infections, or requiring long-term blood transfusion support. Dr North’s project focuses on understanding poor graft function, a potentially life-threatening complication of transplants, by investigating its causes at a cellular level within the bone marrow environment.

By knowing more about why bone marrow transplants fail or result in complications, we can provide better treatments or even prevent them from occurring. This research project is proudly funded by Maddie Riewoldt’s Vision and Haematology Society of Australia and New Zealand.

Related Projects

Steps toward generating new molecular therapies for Bone Marrow Failure Syndromes

2020 – 2024 (Alex Gadomski Scholarship): Steps toward generating new molecular therapies for Bone Marrow Failure Syndromes, Ariel Simpson, Menzies Institute for Medical Research and University of Tasmania. The only established treatment ...

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Towards targeted treatments for Fanconi Anaemia 

2017 – 2019 Fellowship / 2017 Grant-in-Aid, Towards targeted treatments for Fanconi Anaemia, Associate Professor Wayne Crismani, St Vincents Institute for Medical Research Fanconi Anaemia is an inherited disorder which can lead to bone ...

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Identifying therapeutics which can be repurposed for the treatment of Myelodysplastic Syndromes and other bone marrow failure disorders.

2018-2021 (Grant-in-Aid): Identifying therapeutics which can be repurposed for the treatment of Myelodysplastic Syndromes and other bone marrow failure disorders. Associate Professor Amee George, The Australian National University. There are ...

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Precision gene editing for the treatment of Fanconi Anaemia. 

2021-2024 (Grant-in-Aid): Precision gene editing for the treatment of Fanconi Anaemia. Dr Lorna McLeman, St Vincent’s Institute of Medical Research. Fanconi Anaemia is the most common cause of inherited bone marrow failure with a median onset of ...

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