NEAL S. YOUNG, M.D.
CHIEF HAEMATOLOGY BRANCH,
NATIONAL HEART, BLOOD AND LUNG INSTITUTE,
NATIONAL INSTITUTES OF HEALTH (nih), BETHESDA, MARYLAND U.S.A.
Neal S. Young, M.D., is a world expert in the
study of bone marrow failure. His clinical
and research interests include aplastic anemia, telomeropathies and other
inherited bone marrow failure syndromes, myelodysplastic syndromes, paroxysmal
nocturnal hemoglobinuria, and parvovirus B19. His scientific investigations have spanned
basic science and translational research, epidemiology and molecular biology,
and especially pivotal clinical treatment protocols. His work has led to
understanding the pathophysiology of aplastic anemia as immune-mediated and the
development of effective immunotherapy that has dramatically improved survival in
this devastating disease.
Most recently, his group has
discovered that eltrombopag can stimulate hematopoetic stem cells in bone
marrow failure and and that danazo is both effective in the treatment of
telomeropathies and elongates telomeres.
During the course of his career, he
has trained over 100 postdoctoral and clinical fellows and mentored many junior
faculty members. He has published over 500 original research articles,
reviews, book chapters, and monographs.
dr ALISON BERTUCH
associate professor of paediatric haematology/oncology and molecular & human genetics, baylor college of medicine.
Director of the Bone Marrow Failure Program at Texas Children's Hospital
Dr. Bertuch is the director of the Bone
Marrow Failure Program at Texas Children’s Hospital, the largest children’s
hospital and among the top-ranked paediatric haematology/oncology centres in the
United States. She is also Associate Professor of Pediatric Hematology/Oncology
and Molecular & Human Genetics at Baylor College of Medicine. She
has a long-standing interest in telomere biology and her research contributions
have spanned from the basic science of telomeres to translational and clinical
studies on the telomere biology disorders, such as the bone marrow failure predisposition
syndrome dyskeratosis congenita. She is particularly interested in the complexity
of the molecular genetics underlying these disorders.
Bertuch has served in several leadership roles including as a Co-leader of the
Clinical Care Consortium for Telomere Associated Ailments, as an inaugural Executive
Committee member of the North American Pediatric Aplastic Anemia Consortium, and
recent Chairperson of the American Society of Hematology Scientific Committee
on Bone Marrow Failure. She is on the Medical Advisory Board of Team Telomere
and the Scientific Advisory Board of the Shwachman-Diamond Syndrome Registry. She
has received several honors including election to the American Society for
Clinical Investigation and the American Pediatric Society.