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Symposium Program

                                            
The provisional 2 day program is now available

SATURDAY 25TH MAY           Sunday 26TH MAY


DAY 1

Saturday 25th May 
8:45am Welcome

Professor David Ritchie and CEO Nicky Long

Session Chair Professor David Ritchie 

9:05am Introduction to Inherited Bone Marrow Failure Syndromes  (focus on FA and SCN) - Professor Akiko Shimamura
      
9:50am Towards targeted treatments for Fanconi Anaemia - Dr Wayne Crismani
      
10:10am Discovering new genes and mutations that cause failure of bone marrow neutrophil production - Professor Graham Lieschke
      
10:30am Case Studies with panel - FA and SCN

11:00am Morning Tea
SESSION CHAIR Professor ERICA WOOD

11:15am Clinical aspects of Idiopathic Aplastic Anaemia - pathophysiology, current diagnostic strategies, prognostic indicators and treatments - Dr Austin Kulasekararaj
      
12:00pm Update from ’The Australian Aplastic Anaemia Registry - Dr Lucy Fox
      
12:15pm The DIAAMOND study - Avatrombopag in Aplastic Anaemia - Dr Zoe McQuilten
      
12:40pm Predicting malignant transformation of bone marrow failure syndromes using longitudinal targeted sequencing of peripheral blood and cell-free DNA (cf-DNA) - Dr Piers Blombery 

1:00PM LUNCH
SESSION CHAIR Dr LUCY FOX

1:45pm Clinical aspects of MDS - Diagnosis and Management - Professor Akiko Shimamura
      
2:15pm Identification of miRNA biomarkers predictive of clinical outcomes in AA/MDS - Dr Lynette Chee
      
2:30pm Novel Blood Biomarkers for prediciting Bone Marrow Failure in MPN - Dr Belinda Guo
      
2:45pm Clonal haematopoiesis in allogeneic BMTx - Dr Paul Yeh

3:00PM AFTERNOON TEA
SESSION CHAIR dr ANTHEA GREENWAY

3:20pm Using iPSCs to find causes and cures for bone marrow failure in children and young adults - Professor Andrew Elefanty
      
3:40pm Genome editing of haematopoietic stem and progenitor cells to uncover novel therapeutics for aplastic anaemia and other BMFS - Dr Yih-Chih Chan / Professor Mark Dawson
      
4:00pm Case Studies with panel - AA and MDS

5:00pm End of session

Day 2

Sunday 26th May
SESSION CHAIR dr Piers Blombery

9:00am DBA update and Novel Therapeutic Strategies in inherited BMFS (incl. Metformin Study) -  Professor Akiko Shimamura 
      
9:45am Identifying therapeutics which can be repurposed for the treatment of Myelodysplastic Syndromes and other BMF Disorders - Dr Amee George
      
10:00am Genetics of telomeropathies and case studies - Dr Paddy Barbaro 
      
10:30am Melbourne Genomics Health Alliance  BMF Flagship - Dr Lucy Fox 

11:00am - Morning Tea
SESSION CHAIR  Professor  David Ritchie

11:15am PNH clones in BMF patients and recent PNH developments including ravulizumab - Dr Austin Kulasekararaj
      
12:00pm Somatic Mutations in patients with PNH clones - Dr Piers Blombery
      
12:15pm Focus Group - Areas of unmet need, barriers to progression; presentation of planned national prospective multidisciplinary care trial in Australian AA/BMF patients
      
12:50pm Closing comments - Nick Riewoldt

1:00pm - End of Program